Current Clinical Trials
Current Clinical Trials
RDCTN members have extensive expertise in Clinical studies & Research. See below a selection of rare disease clinical trials that are in set-up, ongoing and recently closed from across our network. If you are interested in learning more about the trials listed as currently recruiting please discuss with your clinician in the first instance.
Primary Membranous Nephropathy
Trial Name: A Phase 2b/3 Adaptive, Randomized, Active-controlled Study Evaluating the Efficacy, Safety, and Tolerability of Povetacicept Versus Calcineurin Inhibitor in the Treatment of Primary Membranous Nephropathy.
Stage: Set-up
Principal Investigator: Prof Peter Conlon
Irish Lead: N/A
Sponsor: Vertex
IgA Nephropathy
Trial Name: A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study of Povetacicept in Adults with Immunoglobulin A Nephropathy (RAINIER)
Stage: Closed
Principal Investigator: Prof Peter Conlon
Irish Lead: N/A
Sponsor: Vertex
Epidermolysis Bullosa
Trial Name: EB Shield
Stage: Recruiting
Principal Investigator: Dr Fiona Browne
Irish Lead: Dr Fiona Browne
Sponsor: TWi Biotechnology, Inc.
Progressive Pulmonary Fibrosis
Trial Name: ALOFT- PPF
Stage: Recruiting
Principal Investigator: N/A
Irish Lead: Prof Cormac McCarthy
Sponsor: Bristol-Myers Squibb
Lung Fibrosis
Trial Name: WHISTLE-IPF
Stage: Recruiting
Principal Investigator: N/A
Irish Lead: Prof Michael Keane
Sponsor: Endeavor Biomedicines, Inc
Idiopathic Pulmonary Fibrosis
Trial Name: ALOFT-IPF
Stage: Recruitment closed
Principal Investigator: N/A
Irish Lead: Prof Cormac McCarthy
Sponsor: Bristol-Myers Squibb
Active Idiopathic Inflammatory Myopathy
Trial Name: A Phase 2/3, Randomized, Double-Blinded, Placebo-Controlled, Parallel-Group, 2-Arm, Multicenter, Operationally Seamless Study…
Stage: Recruitment closed
Principal Investigator: Prof Eamonn Molloy
Irish Lead: Prof Bryan Whelan
Sponsor: Argenx
Pulmonary Arterial Hypertension
Trial Name: PROSERA
Stage: Recruitment closed
Principal Investigator: Prof Sean Gaine
Irish Lead: Prof Sean Gaine
Sponsor: Gossamer Bio
Osteogenesis Imperfecta
Trial Name: TOPaZ
Stage: Closed
Sponsor: University of Edinburgh
Familial Paget’s Disease
Trial Name: ZiPP-LTE
Stage: Closed
Sponsor: University of Edinburgh
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